The Molecular Interactome of Synaptogenesis

CABM Researcher Dr. Gaetano Montelione Awarded National Science Foundation Grant for
President Obama's Brain Research through Advancing Innovative Neurotechnologies Initiative

Gaetano Montelione, Distinguished Professor at the Center for Advanced Biotechnology and Medicine and Davide Comoletti, Assistant Professor at the Child Health Institute of New Jersey have been awarded a joint grant entitled “The Molecular Interactome of Synaptogenesis”, one of the National Science Foundation (NSF) Early Concept Grants for Exploratory Research (EAGER). Drs. Montelione and Comoletti will collaborate to apply high throughput cloning and expression technologies in HEK293 cells to discover new protein-protein interactions that regulate neuronal synapse development. The highly competitive two-year $300,000 EAGER awards, part of President Obama's Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative, are aimed at generating transformative insights into understanding the connectivity of the brain. The primary objective of the grant is to provide infrastructure that will have broad scientific and social impacts. The interdisciplinary nature of the EAGER project, at the interface of neurobiology, cell biology, systems biology, bioengineering, bioinformatics, and molecular biophysics, will allow the principal investigators to expand undergraduate research programs, and to proactively recruit undergraduate minority students, training the next generation of molecular neuroscientists. For additional information, please visit the National Science Foundation, The White House BRAIN Initiative, and Montelione Laboratory Websites.